| Date / Time | Away Team | Score | Home Team | Score | |||
|---|---|---|---|---|---|---|---|
| August 27, 2010 - 7:30pm |
 |
Frontier Cougars | 16 | @ |
 |
Shenandoah Zeps | 19 |
| Date / Time | Away Team | Score | Home Team | Score | |||
|---|---|---|---|---|---|---|---|
| September 3, 2010 - 7:30pm |
|
Shenandoah Zeps | 0 | @ |
|
Belpre Golden Eagles | 0 |
| September 10, 2010 - 7:30pm |
|
Shenandoah Zeps | 0 | @ |
 |
Meadowbrook Colts | 0 |
| September 17, 2010 - 7:30pm |
|
Shadyside Tigers | 0 | @ |
|
Shenandoah Zeps | 0 |
| September 24, 2010 - 7:30pm |
|
Barnesville Shamrocks | 0 | @ |
|
Shenandoah Zeps | 0 |
| October 1, 2010 - 7:30pm |
|
Shenandoah Zeps | 0 | @ |
 |
Buckeye Trail Warriors | 0 |
| October 8, 2010 - 7:30pm |
|
Monroe Central Seminoles | 0 | @ |
|
Shenandoah Zeps | 0 |
| October 15, 2010 - 7:30pm |
|
Shenandoah Zeps | 0 | @ |
|
River Pilots | 0 |
| October 22, 2010 - 7:30pm |
|
Shenandoah Zeps | 0 | @ |
|
Fort Frye Cadets | 0 |
| October 29, 2010 - 7:30pm |
 |
Caldwell Redskins | 0 | @ |
|
Shenandoah Zeps | 0 |
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